Advancing Dementia Care Continuity: The 3A (Awareness, Attitude, Action) Framework

Huali Wang^1,#

1. Dementia Care and Research Center, National Clinical Research Center for Mental Disorders (Peking University), National Health Commission (NHC) Key Laboratory for Mental Health, Beijing Municipal Key Laboratory of Translational Research on Diagnosis and Treatment of Dementia, Peking University Institute of Mental Health (Sixth Hospital), Beijing, China.

^# Corresponding author: Huali Wang, huali_wang@bjmu.edu.cn.

In the context of World Alzheimer's Month 2025, this perspective article examines the current state of care continuity for people living with dementia in China and identifies critical gaps in this domain. The article further reviews existing global dementia action plans, highlighting the strategic approaches outlined in China's National Action Plan in response to Dementia. To transform knowledge into meaningful change, this perspective proposes the 3A approach — Awareness, Attitude, and Action — as a comprehensive guiding framework to strengthen and advance the continuum of care.

加强和推进痴呆全程管理：意识-态度-行动（3A）框架

王华丽^1,#

1. 记忆障碍诊疗与研究中心，国家精神心理疾病临床医学研究中心（北京大学），国家卫健委精神卫生重点实验室，痴呆诊治转化医学研究北京市重点实验室，北京大学精神卫生研究所（第六医院），北京，中国。

^# 通讯作者：王华丽, huali_wang@bjmu.edu.cn。

2025年世界阿尔茨海默病月之际，本观点性文章探讨了中国目前针对痴呆患者全程管理的现状，并指出了该领域存在的关键缺口。文章进一步回顾了现有的全球痴呆行动计划，重点介绍了中国《应对老年期痴呆国家行动计划（2024–2030年）》的策略。为了将现有知识转化为切实的改变，本观点性文章提出 "3A方法"，即意识（Awareness）、态度（Attitude）和行动（Action），将其作为加强和推进全程管理的指导框架。

For more information: https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2025.202

National Survey on Nutrition Knowledge Assessment Among Junior High School Students — 31 PLADs, China, 2023–2024

Yujie Qiu¹; Caicui Ding¹; Fan Yuan¹; Tanchun Yu¹; Ailing Liu^1,#

1 National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.

^# Corresponding author: Ailing Liu, liual@ninh.chinacdc.cn.

Nutritional knowledge (NK) is a key modifiable factor influencing the dietary behavior and nutritional status of children. Currently, nationally representative data assessing NK among Chinese junior high school students are unavailable. This study aimed to assess NK levels using recent, nationally representative data from China. A multistage stratified random cluster sampling method was used to select 28,629 junior high school students from 195 survey sites across 31 provincial-level administrative divisions in China. Data were collected using a standardized questionnaire developed using rigorous scientific procedures. NK awareness rates were described as weighted prevalence rates with 95% confidence intervals (95% CIs). Subgroup comparisons were performed using the Rao–Scott chi-square test. The overall NK awareness rate among Chinese junior high school students was 40.0% (95% CI: 36.5–43.5%). The rates for the five dimensions, dietary recommendations, nutrient content of foods, food and health, food choices, and food safety, were 20.1%, 46.2%, 65.3%, 65.2%, and 65.2%, respectively. The analysis revealed significant variations in overall and dimension-specific awareness rates across groups. Males, students from rural and western regions, and students from families with lower socioeconomic status had poorer NK levels than their counterparts. Among the 10 knowledge points with the lowest accuracy rates, seven belonged to dietary recommendations, two to food safety, and one to food and health. NK awareness rates among junior high school students require improvement, especially regarding dietary recommendations, which remain a key component of students' nutrition education. Males, students from rural and western regions, and students from families with lower socioeconomic status should be the key populations for NK dissemination in the future.

初中生营养健康知识水平评估 — 31省，中国，2023–2024年

仇玉洁¹；丁彩翠¹；袁帆¹；於坛春¹；刘爱玲^1,#

1. 营养与健康所，中国疾病预防控制中心，北京，中国。

^# 通信作者：刘爱玲，liual@ninh.chinacdc.cn。

本研究旨在评估我国初中生营养健康知识水平，为落实《健康中国行动（2019–2030年）》中“到2030年居民营养健康知识知晓率较2022年提升10%”的目标提供全国代表性基线数据。采用多阶段分层随机整群抽样的方法，从全国31省的195个调查点抽取28,629名初中生。通过标准化问卷收集数据。使用加权率及95% CI描述营养知识知晓率。采用Rao-Scott²检验进行亚组比较。我国初中生营养健康知识知晓率为40.0%。各维度知晓率从低到高依次为：膳食推荐20.1%、食物分类46.2%、食物与健康65.3%、食物选择65.2%、食品安全65.2%。亚组分析发现，男性、农村和西部地区学生以及家庭社会经济地位较低的学生的知晓率水平较低（P<0.05）。初中生营养健康知识水平仍需提高，应重点加强膳食推荐相关内容普及，并针对男性、农村及西部地区、低社会经济地位学生开展有针对性的营养健康知识普及工作。

For more information: https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2025.204

Curriculum Factors in Real-World Training Scenarios for Improving Intention of Laypersons to Perform Cardiopulmonary Resuscitation — Beijing Municipality, China, 2025

Guixiu Chen^1,2; Lei Hou^2,#; Keyi Quan²; Bo Chen²; Xuefei Feng²; Yibing Ji²; Ning Wang²; Baohua Wang²

1. School of Public Health, Inner Mongolia Medical University, Hohhot City, Inner Mongolia Autonomous Region, China;

2. National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

^# Corresponding author: Lei Hou, houlei@ncncd.chinacdc.cn.

This study aimed to investigate the associations between training curriculum factors and the intention of laypersons to perform cardiopulmonary resuscitation (CPR). We recruited laypersons participating in CPR training programs from nine public training institutes in Beijing, China, between February 15 and July 15, 2025. The exposure variable in this cohort study was trainee feedback on course content, and the primary outcome was a high intention to perform CPR following training. Robust Poisson regression models were used to calculate the incidence rate ratios (RRs) with 95% confidence intervals (CIs). Among 2,035 laypersons enrolled, 74.7% reported high CPR intention following training. This proportion was 42.4% and 96.4% for those with low and high CPR intentions, respectively, before training. Nine curriculum factors with RRs greater than 1.000 were identified. In 817 low-intention laypersons, the coexistence of five to seven factors and eight or nine factors increased the likelihood of high intention by 174.7% (RR, 2.747; 95% CI, 0.964, 7.826) and 283.6% (RR, 3.836; 95% CI, 1.493, 9.857), respectively, compared with exposure to zero to four factors. In 1,218 high-intention laypersons, a dose-response relationship emerged indirectly, as curriculum factors enhanced CPR intention by improving self-efficacy in cardiac arrest recognition and CPR performance. Our study highlighted that key CPR curriculum content is associated with the post-training intention to perform CPR in the real world.

培训课程因素改善非专业人员心肺复苏意愿的真实世界研究 — 北京市，中国，2025年

陈桂秀^1,2；厚磊^2,#；权可伊²；陈波²；冯雪菲²；姬一兵²；王宁²；王宝华²

1. 公共卫生学院，内蒙古医科大学，呼和浩特市，内蒙古自治区，中国；

2. 慢性非传染性疾病预防控制中心，中国疾病预防控制中心，北京，中国。

^# 通讯作者: 厚磊，houlei@ncncd.chinacdc.cn。

本研究探讨心肺复苏（CPR）培训课程因素与旁观者实施CPR意愿的关联关系。2025年2月15日至7月15日在中国北京9所公众培训机构招募参加CPR培训项目的非专业人员构建学员队列。暴露变量根据受训者反馈的课程内容定义，结局定义为培训后受训者报告高CPR实施意愿。采用稳健泊松回归模型计算暴露组和非暴露组的结局发生率比（RR）及其95%可信区间（CI）。在纳入分析的2,035名学员中，74.7%受训后报告高CPR实施意愿；在受训前报告低和高CPR实施意愿的两个亚组中，该率分别为42.4%和96.4%。研究筛选了9个RR大于1.000的与CPR理论和实际操作有关的课程因素。在含有817名学员的受训前低CPR实施意愿亚组中，与存在0–4个课程因素组相比，5–7个和8–9个课程因素共存组受训后高CPR实施意愿率分别增加了174.7%（RR 2.747；95% CI 0.964, 7.826）和283.6%（RR 3.836；95% CI 1.493, 9.857）。在含有1,218名学员的受训前高CPR实施意愿亚组中，剂量-反应关系出现在间接关联路径，即课程因素通过提高学员正确识别心脏骤停和正确实施CPR的自我效能强化CPR实施意愿。真实世界CPR培训中的关键课程因素与学员受训后高CPR意愿存在关联。

For more information: https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2025.205

A Case Report of Dengue Infection After Allogeneic Hematopoietic Stem Cell Transplantation in Patient with Acute B-Lymphoblastic Leukemia — China, 2025

Ying Zhou¹; Chaofeng Sun¹; Qinglian Liu¹; Yuanli Ling¹; Bo Yang^1,#

1. Haizhu District Center for Disease Control and Prevention, Guangzhou City, Guangdong Province, China.

# Corresponding author: Bo Yang, yangbolanbo@gz.gov.cn.

In 2025, a patient with leukemia in Haizhu District, Guangdong Province, China, tested positive for dengue virus. The local Center for Disease Control and Prevention immediately initiated an investigation and response. This investigation included epidemiological surveys, vector mosquito surveillance, case findings, and blood sample collection for laboratory testing. The laboratory analyses comprised dengue virus nucleic acid detection, antigen detection, specific antibody detection, viral isolation, and genetic sequencing. The patient was diagnosed with dengue virus serotype 1 (DENV-1) infection 6 months prior to undergoing chemotherapy and targeted therapy for leukemia. Six months later, during high-intensity immunosuppressive therapy following allogeneic hematopoietic stem cell transplantation, the patient tested positive again for DENV-1. Genetic sequencing revealed 99.99% identity between the viral sequences obtained during initial infection and subsequent detection. Viral culture confirmed the presence of a replication-competent live virus. This is the first documented case of persistent dengue virus infection lasting six months in a patient with leukemia in China. This highlights that for patients undergoing hematopoietic stem cell transplantation and immunosuppressive therapy, particularly in dengue-endemic regions, there should be heightened vigilance regarding the possibility of persistent dengue infection. Implementation of continuous serological monitoring is warranted in high-risk populations.

一例急性B淋巴细胞白血病患者异基因造血干细胞移植后持续性登革病毒感染的病例报告 — 中国，2025年

周莹¹；孙超丰¹；刘青连¹；凌远理¹；杨波^1,#

1. 广州市海珠区疾病预防控制中心，广州，广东省，中国。

^# 通讯作者: 杨波，yangbolanbo@gz.gov.cn。

2025年，中国广东省海珠区发现一例白血病患者登革病毒检测呈阳性，接到报告后当地疾病预防控制中心立即启动调查与响应工作。调查工作包括流行病学调查、媒介蚊虫监测、病例搜索以及血液样本采集。实验室检测涵盖登革病毒(DENV)核酸检测、抗原检测、特异性抗体检测、病毒分离和基因测序。 该患者在六个月前因白血病接受化疗和靶向治疗期间，首次确诊感染DENV-1；六个月后，在进行异基因造血干细胞移植后的高强度免疫抑制治疗期间，再次检测出DENV-1核酸阳性。全基因组测序显示，此次感染的病毒序列与初次感染的病毒序列一致性达99.99%。病毒培养证实存在具有复制能力的活病毒。本研究报道了一例白血病患者体内DENV持续感染达六个月的病例。研究结果表明，对于接受造血干细胞移植及免疫抑制治疗的患者，特别是在登革热流行地区，应高度重视DENV持续性感染的可能性，建议对此类高风险人群实施持续血清学监测（如IgM/IgG抗体检测）。

For more information: https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2025.206