Liwen Hu; Lyubo Tian; Ke Yan; Shuang Zhang; Wenjun Xie; Jing Feng; Xunbo Du; Liang Wang; Weixuan Liu; Junrong Luo; Fengzhu Tang; Ning Yang; Yao Wang; Yun Peng; Zhenhua Chen; Qing Zhang; Jiantong Meng; Rong Lu; Liwen Hu; Lyubo Tian; Ke Yan; Shuang Zhang; Wenjun Xie; Jing Feng; Xunbo Du; Liang Wang; Weixuan Liu; Junrong Luo; Fengzhu Tang; Ning Yang; Yao Wang; Yun Peng; Zhenhua Chen; Qing Zhang; Jiantong Meng; Rong Lu

doi:10.46234/ccdcw2026.063

[1]

Sharp TM, Fischer M, Muñoz-Jordán JL, Paz-Bailey G, Staples JE, Gregory CJ, et al. Dengue and Zika virus diagnostic testing for patients with a clinically compatible illness and risk for infection with both viruses. MMWR Recomm Rep 2019;68(1):1 − 10. https://doi.org/10.15585/mmwr.rr6801a1.

[2]

World Health Organization. Dengue. 2025. https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue. [2026-01-27].

[3]

World Health Organization. Zika virus. 2025. https://www.who.int/news-room/fact-sheets/detail/zika-virus. [2026-01-27].

[4]

Lin DCD, Weng SC, Tsao PN, Chu JJH, Shiao SH. Co-infection of dengue and Zika viruses mutually enhances viral replication in the mosquito Aedes aegypti. Parasit Vectors 2023;16(1):160. https://doi.org/10.1186/s13071-023-05778-1.

[5]

Ngwe Tun MM, Nwe KM, John JL, Mumo M, Manah AM, Takamatsu Y, et al. Molecular and serological detection of Zika virus and Zika-dengue virus coinfections in febrile patients in Sabah, Malaysia, 2019-2020. Am J Trop Med Hyg 2025;113(6):1380 − 4. https://doi.org/10.4269/ajtmh.25-0066.

[6]

Khongwichit S, Chuchaona W, Vongpunsawad S, Poovorawan Y. Molecular surveillance of arboviruses circulation and co-infection during a large chikungunya virus outbreak in Thailand, October 2018 to February 2020. Sci Rep 2022;12(1):22323. https://doi.org/10.1038/s41598-022-27028-7.

[7]

Chia PY, Yew HS, Ho H, Chow A, Sadarangani SP, Chan M, et al. Clinical features of patients with Zika and dengue virus co-infection in Singapore. J Infect 2017;74(6):611 − 5. https://doi.org/10.1016/j.jinf.2017.03.007.

[8]

Zhou CM, Liu JW, Qi R, Fang LZ, Qin XR, Han HJ, et al. Emergence of Zika virus infection in China. PLoS Negl Trop Dis 2020;14(5):e0008300. https://doi.org/10.1371/journal.pntd.0008300.

[9]

Zhang S, Wu JL, Wang D, Song JD, Li Y, Yin CH, et al. The first imported case of Zika virus infection - Shandong Province, China, 2025. China CDC Wkly 2025;7(30):1004 − 8. https://doi.org/10.46234/ccdcw2025.169.

[10]

Phadungsombat J, Nakayama EE, Shioda T. Unraveling dengue virus diversity in Asia: an epidemiological study through genetic sequences and phylogenetic analysis. Viruses 2024;16(7):1046. https://doi.org/10.3390/v16071046.

[11]

Gao DZ, Lou YJ, He DH, Porco TC, Kuang Y, Chowell G, et al. Prevention and control of Zika as a mosquito-borne and sexually transmitted disease: a mathematical modeling analysis. Sci Rep 2016;6(1):28070. https://doi.org/10.1038/srep28070.

[12]

Lobkowicz L, Ramond A, Sanchez Clemente N, de Alencar Ximenes RA, de Barros Miranda-Filho D, Montarroyos UR, et al. The frequency and clinical presentation of Zika virus coinfections: a systematic review. BMJ Glob Health 2020;5(5):e002350. https://doi.org/10.1136/bmjgh-2020-002350.

[13]

Vogels CBF, Rückert C, Cavany SM, Perkins TA, Ebel GD, Grubaugh ND. Arbovirus coinfection and co-transmission: a neglected public health concern? PLoS Biol 2019;17(1):e3000130. http://dx.doi.org/10.1371/journal.pbio.3000130.